5 ESSENTIAL ELEMENTS FOR NR1-SITE

Using this tactic, Kalbaugh et al. assigned affinity and efficacy roles to positions while in the LBDs in the NR1 and NR2A NMDAR subunits. In situ mutation of residues in immediate connection with certain ligand afflicted the two efficacy and affinity, although positions that stabilize the closed cleft conformation without having a direct ligand in